markboguski.net

Home   Education   Employment   Publications   Presentations   Boards   Teaching   Awards
 

Neurogenomics       

Publications

  • Neurogenomics: At the Intersection of Neurobiology and Genome Sciences (2004) |PubMed|PDF| The last ten years of the 20th century was the Decade of the Brain.  The Human Genome Project began in 1990 and produced a nearly complete working draft by the year 2000.  Despite the simultaneity of these ambitious research programs, "brains were brains and genes were genes and rarely the twain did meet" (apologies to Rudyard Kipling)  The time seemed ripe to begin a 21st century unification of genomics and neuroscience with one goal being to understand how “only” about 24,000 human genes contribute to the development, structure and functions of an organ containing more than a hundred billion neurons with up to a million billion estimated connections.  The successful creation of a new field of neurogenomics was not only dependent on new technologies and research strategies, but also on creating a cultural bridge between genome scientists and neuroscientists, two groups with markedly different histories and research styles.  One way to do this was to launch a cross-disciplinary project of sufficient scope and potential impact that it could galvanize both research communities.
  • Genome-Wide Atlas of Gene Expression in the Adult Mouse Brain (2007) |PubMed|PDF|

Presentations

  • Intersections of Genomics, Bioinformatics and Neuroscience. Neurogenomics Research Symposium at the Society for  Neuroscience 33rd Annual Meeting. New Orleans, LA.  November 6, 2003
  • Neurogenomics and the Allen Brain Atlas. A Decade of Neuroscience Informatics: Looking Ahead.  National Institutes of Health, Bethesda, MD.  April 26, 2004 |Mental Health|PDF|

Popular Press

In my capacity as the founding director of the Allen Brain Atlas project and the Allen Institute for Brain Science, I had the great privilege of assisting Paul Allen and Jody Patton in the important early work of the Institute.

  • Conducted planning charettes and feasibility studies for the Institute and Atlas
  • Formed a Scientific Advisory Board
  • Identified, recruited and hired key staff in neuroanatomy (Hong-Wei Dong), informatics (Mike Hawrylyz), genomics (Lin Chen), automation engineering (Paul Wohnoutka), technology (Chinh Dang) and operations (Allan Jones)
  • Identified and transferred or in-licensed key enabling technologies
  • Located, established and supervised initial build-out of Fremont research facility
  • Launched the inaugural (Brain Atlas) project
  • Helped to secure IRS status for the Institute as a not-for-profit Medical Research Organization
  • Lobbied on Capitol Hill and at NIH for Federal support
  • Initiated collaboration discussions with the Nature Publishing Group that led to the Nature Neuroscience Gateway
  • Helped to design and execute the formal launch plan and represented the Institute to the popular press and scientific and medical communities
     

Home   Education   Employment   Publications   Presentations   Boards   Teaching   Awards

 

 

 

 

 

 

 
 

 

© Dr. Mark S. Boguski, All rights reserved