Neuwelt, E. A., Boguski, M. S., et al. (1978). "Possible sites of origin of human plasma ribonucleases as evidenced by isolation and partial characterization of ribonucleases from several human tissues." Cancer Res 38(1): 88-93. |PubMed|PDF| 

Karpetsky, T. P., Boguski, M. S., et al. (1979). "Structures, properties, and possible biologic functions of polyadenylic acid." Subcell Biochem 6: 1-116. |PuBMed|PDF| 

Boguski, M. S., Hieter, P. A., et al. (1980). "Identification of a cytidine-specific ribonuclease from chicken liver." J Biol Chem 255(5): 2160-3. |PubMed|PDF|

Boguski, M. S., Elshourbagy, N., et al. (1984). "Rat apolipoprotein A-IV contains 13 tandem repetitions of a 22-amino acid segment with amphipathic helical potential." Proc Natl Acad Sci U S A 81(16): 5021-5. |PubMed|PDF| This work, carried out when I was Jeff Gordon’s first graduate student, not only provided some surprising and valuable insights in the field of apolipoprotein molecular biology but also dramatically changed the direction of my career into a field that would, a decade later, finally get a name: bioinformatics.  When I first cloned and sequenced the cDNA for apoAIV from intestinal epithelial cells, it was not very obvious what experiments to do to elucidate its function.  As I scoured the literature for ideas, I can across a 1977 paper by the evolutionary biologist, Walter Fitch, who was studying phylogeny reconstruction using protein sequence data (very little of which was actually available at the time).  Fitch noticed “internal homology” in apoAI and proposed that these internal repeats corresponded to a series of amphipathic α–helices that might be the structural basis for apoAI’s ability to bind lipids yet remain soluble.  These internal repeats in apoAI were also discovered independently by Andrew McLachlan (1977) using FORTRAN programs he had written to analyze sequence periodicities in myosins.  Hypothesizing that apoAIV might share some structural features with apoAI, I wrote to McLachlan at the MRC in Cambridge, U.K. who generously sent me his FORTRAN code on magnetic tape and I got permission from our department’s crystallography lab to compile and run this software on the only computer in my department at the time, a DEC VAX 11/780.  Analysis of the apoAIV sequence also showed a strong pattern of internal repeats.  I also obtained a very early version of GenBank (Release 14, November 1983, containing 2.3 million bases from ~2,400 sequences) and performed a homology search which showed that apoAIV was closely related to apoAI.  The results and conclusions of this work constitute the subject matter of this paper and a series of related publications over the next several years (e.g. Boguski et al., 1985; Boguski et al., 1986).  Through this work, I developed a research paradigm based on the principles that sequence analysis could predict both structure and function (as testable hypotheses) and also provide insights into the genomic organization and evolution of gene families.  I have successfully applied this approach time and again throughout various chapters of my research career.  A particularly notable example is our successful prediction of the unexpected structure and general function of leptin in 1995.  Recent work by other groups has demonstrated a relationship between apoAIV and leptin that I could never have imagined back in 1984 or 1995, namely that apoAIV is a circulating satiety factor expressed in the hypothalamus where it appears to be regulated by leptin! (Shen et al., 2007, Tso and Liu, 2004)

Elshourbagy, N. A., Boguski, M. S., et al. (1985). "Expression of rat apolipoprotein A-IV and A-I genes: mRNA induction during development and in response to glucocorticoids and insulin." Proc Natl Acad Sci U S A 82(23): 8242-6. |PubMed|PDF| 

Lowe, J. B., Boguski, M. S., et al. (1985). "Human liver fatty acid binding protein. Isolation of a full length cDNA and comparative sequence analyses of orthologous and paralogous proteins." J Biol Chem 260(6): 3413-7.|PubMed|PDF| 

Boguski, M. S., Elshourbagy, N., et al. (1985).|PubMed|PDF| "Comparative analysis of repeated sequences in rat apolipoproteins A-I, A-IV, and E." Proc Natl Acad Sci U S A 82(4): 992-6. |PubMed|PDF| 

Boguski, M. S., Freeman, M., et al. (1986). "On computer-assisted analysis of biological sequences: proline punctuation, consensus sequences, and apolipoprotein repeats." J Lipid Res 27(10): 1011-34.|PubMed|PDF| 

Boguski, M. S., Birkenmeier, E. H., et al. (1986). "Evolution of the apolipoproteins. Structure of the rat apo-A-IV gene and its relationship to the human genes for apo-A-I, C-III, and E." J Biol Chem 261(14): 6398-407.|PubMed|PDF| 

Elshourbagy, N. A., Walker, D. W., et al. (1986). "The nucleotide and derived amino acid sequence of human apolipoprotein A-IV mRNA and the close linkage of its gene to the genes of apolipoproteins A-I and C-III." J Biol Chem 261(5): 1998-2002.|PubMed|PDF| 

Boguski, M. S., Elshourbagy, N. A., et al. (1986). "Rat apolipoprotein A-IV: application of computational methods for studying the structure, function, and evolution of a protein." Methods Enzymol 128: 753-73. |PubMed|PDF|

Boguski, M. S., Birkenmeier, E. H., et al. (1986). Structure and systematics of the rat apo-A-IV gene: evolution of the mammalian apolipoproteins. Atherosclerosis VII. N. H. Fidge and P. J. Nestel. Amsterdam, Elsevier. 696: 139-142.

Cole, K. D., Fernando-Warnakulasuriya, G. P., et al. (1987). "Primary structure and comparative sequence analysis of an insect apolipoprotein. Apolipophorin-III from Manduca sexta." J Biol Chem 262(24): 11794-800.|PubMed|PDF| 

Elshourbagy, N. A., Walker, D. W., et al. (1987). "Structure and expression of the human apolipoprotein A-IV gene." J Biol Chem 262(17): 7973-81.|PubMed|PDF| 

Kanost, M. R., Boguski, M. S., et al. (1988). "Primary structure of apolipophorin-III from the migratory locust, Locusta migratoria. Potential amphipathic structures and molecular evolution of an insect apolipoprotein." J Biol Chem 263(22): 10568-73.|PubMed|PDF| 

Ballester, R., Marchuk, D., et al. (1990). "The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins." Cell 63(4): 851-9. |PubMed|PDF| 

Opipari, A. W., Jr., Boguski, M. S., et al. (1990). "The A20 cDNA induced by tumor necrosis factor alpha encodes a novel type of zinc finger protein." J Biol Chem 265(25): 14705-8.|PubMed|PDF| 

Boguski, M. S., Sikorski, R. S., et al. (1990). "Expanding family." Nature 346(6280): 114.|PubMed|PDF| 

Benson, D., Boguski, M., et al. (1990). "The National Center for Biotechnology Information." Genomics 6(3): 389-91.|PubMed|PDF| 

Peitsch, M. C. and Boguski, M. S. (1990). "Is apolipoprotein D a mammalian bilin-binding protein?" New Biol 2(2): 197-206.|PubMed|PDF| 

Trainor, C. D., Evans, T., et al. (1990). "Structure and evolution of a human erythroid transcription factor." Nature 343(6253): 92-6.|PubMed|PDF|

Sikorski, R. S., Boguski, M. S., et al. (1990). "A repeating amino acid motif in CDC23 defines a family of proteins and a new relationship among genes required for mitosis and RNA synthesis." Cell 60(2): 307-17.|PubMed|PDF| 

Marchuk, D. A., Saulino, A. M., et al. (1991). "cDNA cloning of the type 1 neurofibromatosis gene: complete sequence of the NF1 gene product." Genomics 11(4): 931-40.|PubMed|PDF| 

Peitsch, M. C. and Boguski, M. S. (1991). "The first lipocalin with enzymatic activity." Trends Biochem Sci 16(10): 363.|PubMed|PDF| 

Wang, Y., Boguski, M., et al. (1991). "sar1, a gene from Schizosaccharomyces pombe encoding a protein that regulates ras1." Cell Regul 2(6): 453-65.|PubMed|PDF| 

Sikorski, R. S., Michaud, W. A., et al. (1991). TPR proteins as essential components of the yeast cell cycle. Cold Spring Harb Symp Quant Biol. 56 The Cell Cycle: 663-73.

Kinzler, K. W., Nilbert, M. C., et al. (1991). "Identification of FAP locus genes from chromosome 5q21." Science(5020): 661-665.|PubMed|PDF|

Boguski, M. S., Bairoch, A., et al. (1992). "Proto-vav and gene expression." Nature 358(6382): 113.|PubMed|PDF|

States, D. J. and Boguski, M. S. (1991). Homology and Similarity. Sequence Analysis Primer. M. Gribskov and J. Devereux. New York, W.H. Freeman: 90-157. |Front Cover|Back Cover|

Boguski, M. S. (1992). "Computational sequence analysis revisited: new databases, software tools, and the research opportunities they engender." J Lipid Res 33(7): 957-74.|PubMed|PDF| 

Duronio, R. J., Gordon, J. I., et al. (1992). "Comparative analysis of the beta transducin family with identification of several new members including PWP1, a nonessential gene of Saccharomyces cerevisiae that is divergently transcribed from NMT1." Proteins 13(1): 41-56.|PubMed|PDF| 

Boguski, M. S., Murray, A. W., et al. (1992). "Novel repetitive sequence motifs in the alpha and beta subunits of prenyl-protein transferases and homology of the alpha subunit to the MAD2 gene product of yeast." New Biol 4(4): 408-11.|PubMed|PDF| 

Boguski, M. S., Hardison, R. C., et al. (1992). "Analysis of conserved domains and sequence motifs in cellular regulatory proteins and locus control regions using new software tools for multiple alignment and visualization." New Biol 4(3): 247-60.|PubMed|PDF| 

Boguski, M. S. (1992). "A molecular biologist visits Jurassic Park." Biotechniques 12(5): 668-669. |PDF|

Boguski, M. S., Ostell, J., et al. (1992). Molecular Sequence Databases and their Uses. Protein Engineering: a Practical Approach. A. R. Rees, R. Wetzel and M. J. E. Sternberg. Oxford, Oxford University Press: 57-88.|Front Cover|Back Cover|

Boguski, M. S. and McCormick, F. (1993). "Proteins regulating Ras and its relatives." Nature 366(6456): 643-54.|PubMed|PDF| 

Tugendreich, S., Boguski, M. S., et al. (1993). "Linking yeast genetics to mammalian genomes: identification and mapping of the human homolog of CDC27 via the expressed sequence tag (EST) data base." Proc Natl Acad Sci U S A 90(21): 10031-5.|PubMed|PDF| 

Lawrence, C. E., Altschul, S. F., et al. (1993). "Detecting subtle sequence signals: a Gibbs sampling strategy for multiple alignment." Science 262(5131): 208-14.|PubMed|PDF| 

Boguski, M. S., Lowe, T. M., et al. (1993). "dbEST--database for "expressed sequence tags"." Nat Genet 4(4): 332-3. |PubMed|PDF|

Gregory, P. E., Gutmann, D. H., et al. (1993). "Neurofibromatosis type 1 gene product (neurofibromin) associates with microtubules." Somat Cell Mol Genet 19(3): 265-74.|PubMed|PDF| 

Lai, C. C., Boguski, M., et al. (1993). "Influence of guanine nucleotides on complex formation between Ras and CDC25 proteins." Mol Cell Biol 13(3): 1345-52.|PubMed|PDF|

Waldherr, M., Ragnini, A., et al. (1993). "MRS6--yeast homologue of the choroideraemia gene." Nat Genet 3(3): 193-4. |PubMed|PDF|

Gutmann, D. H., Boguski, M., et al. (1993). "Analysis of the neurofibromatosis type 1 (NF1) GAP-related domain by site-directed mutagenesis." Oncogene 8(3): 761-9.|PubMed|PDF| 

Hu, H. M., O'Rourke, K., et al. (1994). "A novel RING finger protein interacts with the cytoplasmic domain of CD40." J Biol Chem 269(48): 30069-72.|PubMed|PDF| 

Boguski, M. S., Tolstoshev, C. M., et al. (1994). "Gene discovery in dbEST." Science 265(5181): 1993-4. |PubMed|PDF|

Benson, D. A., Boguski, M., et al. (1994). "GenBank." Nucleic Acids Res 22(17): 3441-4.|PubMed|PDF| 

Miller, W. and Boguski, M. (1994). "A note about computing all local alignments." Comput Appl Biosci 10(4): 455-6.|PubMed|PDF| 

Boguski, M. S. (1994). "Bioinformatics." Curr Opin Genet Dev 4(3): 383-8. |PubMed|PDF|

Altschul, S. F., Boguski, M. S., et al. (1994). "Issues in searching molecular sequence databases." Nat Genet 6(2): 119-29.|PubMed|PDF| 

Boguski, M. and McEntyre, J. (1994). "I think therefore I publish." Trends Biochem Sci 19(2): 71.|PubMed|PDF| 

Tugendreich, S., Bassett, D. E., Jr., et al. (1994). "Genes conserved in yeast and humans." Hum Mol Genet 3 Spec No: 1509-17. |PubMed|PDF|

Miller, W., Boguski, M., et al. (1994). "Constructing aligned sequence blocks." J Comput Biol 1(1): 51-64.|PubMed|PDF| 

Madej, T., Boguski, M. S., et al. (1995). "Threading analysis suggests that the obese gene product may be a helical cytokine." FEBS Lett 373(1): 13-8. |PubMed|PDF|

Boguski, M. S. (1995). "Hunting for genes in computer data bases." N Engl J Med 333(10): 645-7. |PubMed|PDF|

Bassett, D. E., Jr., Boguski, M. S., et al. (1995). "Comparative genomics, genome cross-referencing and XREFdb." Trends Genet 11(9): 372-3. |PubMed|PDF|

Boguski, M. S. and Schuler, G. D. (1995). "ESTablishing a human transcript map." Nat Genet 10(4): 369-71. |PubMed|PDF|

Boguski, M. S. (1995). "The turning point in genome research." Trends Biochem Sci 20(8): 295-6. |PubMed|PDF|

Jiang, X. C., Bruce, C., et al. (1995). "Point mutagenesis of positively charged amino acids of cholesteryl ester transfer protein: conserved residues within the lipid transfer/lipopolysaccharide binding protein gene family essential for function." Biochemistry 34(21): 7258-63.|PubMed|PDF| 

Boguski, M. S. (1995). "How to make discoveries in molecular sequence databases." FASEB Journal 9(6): A1259.

Boguski, M. S. and Ouellette, B.F.F. (1995). Internet Basics for Biologists. Current Protocols in Molecular Biology. New York, John Wiley & Sons.

Ouellette, B. F. F. and Boguski, M. S. (1995). Sequence Databases: Information Retrieval and Data Submission. Current Protocols in Molecular Biology. New York, John Wiley & Sons.

Boguski, M. S. (1995). "Adventures in information space - biomedical discoveries in a molecular sequence milieu." Serials Librarian 25(3-4): 125-131.

Schuler, G. D., Boguski, M. S., et al. (1995). Sequence Similarity Searching using the BLAST Family of Programs. Current Protocols in Molecular Biology. New York, John Wiley & Sons.

Boguski, M. S., Cox, D. R., et al. (1996). "Genomes and evolution." Curr Opin Genet Dev 6(6): 683-5.|PubMed|PDF| 

Schuler, G. D., Boguski, M. S., et al. (1996). "Genome maps 7. The human transcript map. Wall chart." Science 274(5287): 547-62. |PubMed|PDF|

Schuler, G. D., Boguski, M. S., et al. (1996). "A gene map of the human genome." Science 274(5287): 540-6. |PubMed|PDF| 

Makalowski, W., Zhang, J., et al. (1996). "Comparative analysis of 1196 orthologous mouse and human full-length mRNA and protein sequences." Genome Res 6(9): 846-57. |PubMed|PDF|

Boguski, M., Chakravarti, A., et al. (1996). "The end of the beginning: the race to begin human genome sequencing." Genome Res 6(9): 771-2.|PubMed|PDF| 

Gastier, J. M., Brody, T., et al. (1996). "Development of a screening set for new (CAG/CTG)n dynamic mutations." Genomics 32(1): 75-85.|PubMed|PDF| 

Bassett, D. E., Jr., Boguski, M. S., et al. (1996). "Yeast genes and human disease." Nature 379(6566): 589-90.|PubMed|PDF|

Benson, D. A., Boguski, M., et al. (1996). "GenBank." Nucleic Acids Res 24(1): 1-5.|PubMed|PDF| 

Hudson, T., Stein, L., et al. (1996). "An STS-based map of the human genome." American Journal of Human Genetics 59(4 SUPPL.): A26.

Boguski, M. S. (1996). "Adventures in information space: Genbank, genomes and a turning point in biomedical research." Journal of Investigative Medicine 44(3): 323A

Bassett, D. E., Jr., Boguski, M. S., et al. (1996). "XREFdb: Cross-referencing genes, genetics and mammalian genomes." American Journal of Human Genetics 59(4 SUPPL.): A27.

Hieter, P. and Boguski, M. (1997). "Functional genomics: it's all how you read it." Science 278(5338): 601-2. |PubMed|PDF|

Manickam, P., Guru, S. C., et al. (1997). "Eighteen new polymorphic markers in the multiple endocrine neoplasia type 1 (MEN1) region." Hum Genet 101(1): 102-8.|PubMed|PDF| 

Ouellette, B. F. and Boguski, M. S. (1997). "Database divisions and homology search files: a guide for the perplexed." Genome Res 7(10): 952-5.|PubMed|PDF| 

Guru, S. C., Agarwal, S. K., et al. (1997). "A transcript map for the 2.8-Mb region containing the multiple endocrine neoplasia type 1 locus." Genome Res 7(7): 725-35.|PubMed|PDF| 

Guru, S. C., Olufemi, S. E., et al. (1997). "A 2.8-Mb clone contig of the multiple endocrine neoplasia type 1 (MEN1) region at 11q13." Genomics 42(3): 436-45.|PubMed|PDF| 

Mushegian, A. R., Bassett, D. E., Jr., et al. (1997). "Positionally cloned human disease genes: patterns of evolutionary conservation and functional motifs." Proc Natl Acad Sci U S A 94(11): 5831-6.|PubMed|PDF| 

Chandrasekharappa, S. C., Guru, S. C., et al. (1997). "Positional cloning of the gene for multiple endocrine neoplasia-type 1." Science 276(5311): 404-7.|PubMed|PDF| 

Bassett, D. E., Jr., Boguski, M. S., et al. (1997). "Genome cross-referencing and XREFdb: implications for the identification and analysis of genes mutated in human disease." Nat Genet 15(4): 339-44. |PubMed|PDF|

Bassett, D. E., Jr., Boguski, M., et al. (1997). "Identifying human homologs of cell cycle genes using dbEST and XREFdb." Methods Enzymol 283: 128-40. |PubMed|PDF|

Benson, D. A., Boguski, M. S., et al. (1997). "GenBank." Nucleic Acids Res 25(1): 1-6.|PubMed|PDF| 

Baxevanis, A. D., Boguski, M. S., et al. (1997). Computational analysis of DNA and protein sequences. Genome analysis: A laboratory manual. B. Birren, E. Green, S. Klapholz, R. M. Myers and J. Roskams. Cold Spring Harbor, NY, Cold Spring Harbor Laboratory Press. Vol. 1. Analyzing DNA: 533-586.

Dokken, C. G., Green, E. D., et al. (1997). "Narrowing the critical interval and screening candidates for CCM1 a gene for familial cerebral cavernous malformations." Epilepsia 38(SUPPL. 8): 201-202.

Jia, L., Wilkin, D. J., et al. (1997). "SGAP: The skeletal genome anatomy project." American Journal of Human Genetics 61(4 SUPPL.): A378.

Ross, D. T., Eisen, M., et al. (1997). "Use of a 10,000 gene cDNA microarray to analyze gen    expression patterns in hematological disorders." Blood 90(10 SUPPL. 1 PART 1): 557A

Goodman, L., Boguski, M., et al. (1997). "Genome horizons." Genome Res 7(6): 567.

Deloukas, P., Schuler, G. D., et al. (1998). "A physical map of 30,000 human genes." Science 282(5389): 744-6. |PubMed|PDF|

Ermolaeva, O., Rastogi, M., et al. (1998). "Data management and analysis for gene expression arrays." Nat Genet 20(1): 19-23. |PubMed|PDF|

Makalowski, W. and Boguski, M. S. (1998). "Synonymous and nonsynonymous substitution distances are correlated in mouse and rat genes." J Mol Evol 47(2): 119-21.|PubMed|PDF| 

Makalowski, W. and Boguski, M. S. (1998). "Evolutionary parameters of the transcribed mammalian genome: an analysis of 2,820 orthologous rodent and human sequences." Proc Natl Acad Sci U S A 95(16): 9407-12. |PubMed|PDF|

Wheelan, S. J. and Boguski, M. S. (1998). "Late-night thoughts on the sequence annotation problem." Genome Res 8(3): 168-9. |PubMed|PDF|

Benson, D. A., Boguski, M. S., et al. (1998). "GenBank." Nucleic Acids Res 26(1): 1-7.|PubMed|PDF| http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9399790

Bittner, M., Chen, Y., et al. (1998). "Implementing quantitative analysis of gene expression with microarrays." Cytometry(SUPPL. 9): 26.

Boguski, M. S. (1998). "Bioinformatics - a new era." Trends Guide to Bioinformatics (Suppl S): 1-3. |PubMed|PDF|

Brownstein, M. J., Trent, J. M., et al. (1998). "Functional Genomics." Trends Guide to Bioinformatics (Suppl S): 27-29. |PuBMed|PDF|

Guru, S. C., Manickam, P., et al. (1998). "Identification and characterization of the multiple endocrine neoplasia type 1 (MEN1) gene." Journal of Internal Medicine, 1998.(6): 433-439.

Krizman, D., Schuler, G., et al. (1998). "cDNA libraries from microdissected tissue: Implications for prostate cancer progression." Proceedings of the American Association for Cancer Research Annual Meeting 259: 2599.

Wheelan, S. J., Boguski, M. S., et al. (1999). "Human and nematode orthologs--lessons from the analysis of 1800 human genes and the proteome of Caenorhabditis elegans." Gene 238(1): 163-70.|PubMed|PDF| 

Sahoo, T., Johnson, E. W., et al. (1999). "Mutations in the gene encoding KRIT1, a Krev-1/rap1a binding protein, cause cerebral cavernous malformations (CCM1)." Hum Mol Genet 8(12): 2325-33.|PubMed|PDF| 

Boguski, M. S. (1999). "Biosequence exegesis." Science 286(5439): 453-5. |PubMed|PDF| 

Nusbaum, C., Slonim, D. K., et al. (1999). "A YAC-based physical map of the mouse genome." Nat Genet 22(4): 388-93.|PubMed|PDF| 

Kuehl, P. M., Weisemann, J. M., et al. (1999). "An effective approach for analyzing "prefinished" genomic sequence data." Genome Res 9(2): 189-94.|PubMed|PDF| 

Walker, D. R., Bond, J. P., et al. (1999). "Evolutionary conservation and somatic mutation hotspot maps of p53: correlation with p53 protein structural and functional features." Oncogene 18(1): 211-8.|PubMed|PDF| 

Bassett, D. E., Jr., Eisen, M. B., et al. (1999). "Gene expression informatics--it's all in your mine." Nat Genet 21(1 Suppl): 51-5.|PubMed|PDF|

Pickeral, O. K. and Boguski, M. S. (1999). "The Bioinformatics Bookshelf: Teach Yourself Bioinformatics." Cell 96(4): 451-455 |PubMed|PDF|

Iyer, V. R., Eisen, M. B., et al. (1999). "The transcriptional program in the response of human fibroblasts to serum." Science 283(5398): 83-7. |PubMed|PDF|

Boguski, M., Kim, S., et al. (1999). "Connecting the dots." Nature Genetics, 1999.(3): 249-252.

Krizman, D., Emmert-Buck, M., et al. (1999). "Update on the cancer genome anatomy project: Gene expression profiling of prostate cancer progression." Proceedings of the American Association for Cancer Research Annual Meeting 93: 933.

Benson, D. A., Boguski, M. S., et al. (1999). "GenBank." Nucleic Acids Res 27(1): 12-7.|PubMed|PDF| 

Shatkay, H., Edwards, S., et al. (2000). "Genes, themes and microarrays: using information retrieval for large-scale gene analysis." Proc Int Conf Intell Syst Mol Biol 8: 317-28.|PubMed|PDF| 

Pickeral, O. K., Li, J. Z., et al. (2000). "Classical oncogenes and tumor suppressor genes: a comparative genomics perspective." Neoplasia 2(3): 280-6.|PubMed|PDF| 

Fortini, M. E., Skupski, M. P., et al. (2000). "A survey of human disease gene counterparts in the Drosophila genome." J Cell Biol 150(2): F23-30.|PubMed|PDF| 

Pickeral, O. K., Makalowski, W., et al. (2000). "Frequent human genomic DNA transduction driven by LINE-1 retrotransposition." Genome Res 10(4): 411-5.|PubMed|PDF| 

Ploger, R., Zhang, J., et al. (2000). "XREFdb: cross-referencing the genetics and genes of mammals and model organisms." Nucleic Acids Res 28(1): 120-2.|PubMed|PDF|

Rubin, G. M., Yandell, M. D., et al. (2000). "Comparative genomics of the eukaryotes." Science 287(5461): 2204-15.|PubMed|PDF|  

Zhang, J., Kuehl, P., et al. (2001). "The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants." Pharmacogenetics 11(7): 555-72. |PubMed|PDF| 

Kuehl, P., Zhang, J., et al. (2001). "Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression." Nat Genet 27(4): 383-91.|PubMed|PDF| 

Shoemaker, D. D., Schadt, E. E., et al. (2001). "Experimental annotation of the human genome using microarray technology." Nature 409(6822): 922-7.|PubMed|PDF|  

Boguski, M. S. (2002). "Comparative genomics: the mouse that roared." Nature 420(6915): 515-6. |PubMed|PDF|

Shatkay, H., Edwards, S., et al. (2002). "Information Retreival Meets Gene Analysis." IEEE Intelligent Systems in Biology 17(2): 45-53. |IEEE|PDF|

Szak, S. T., Pickeral, O. K., et al. (2002). "Molecular archeology of L1 insertions in the human genome." Genome Biol 3(10): research0052. |PuBMed|PDF|

Winslow, R. L. and Boguski, M. S. (2003). "Genome informatics: current status and future prospects." Circ Res 92(9): 953-61.|PubMed|PDF|

Boguski, M. S. and McIntosh, M. W. (2003). "Biomedical informatics for proteomics." Nature 422: 233-7. |PubMed|PDF|

Boguski, M. S. (2003). "Coming attractions." Genomics 82(6): 583. |PubMed|PDF|

Boguski, M. S. (2003). "The only thing permanent is change." Genomics 82(3): 253.|PubMed|PDF|

Schuetz, E. G., Relling, M. V., et al. (2004). "PharmGKB update: II. CYP3A5, cytochrome P450, family 3, subfamily A, polypeptide 5." Pharmacol Rev 56(2): 159. |PubMed|PDF| 

Boguski, M. S. (2004). "ENCODE and ChIP-chip in the genome era." Genomics 83(3): 347-8. |PubMed|PDF|

Boguski, M. S. and Jones, A. R. (2004). "Neurogenomics: at the intersection of neurobiology and genome sciences." Nat Neurosci 7(5): 429-33. |PubMed|PDF|

Voshol, H. Cho, C.R., et al. (2006), “Systems Biology: Integrating in silico approached and experimental approaches to study signaling networks” in Systems Biology: a User’s Guide, a Focus issue of Nature Cell Biology and Nature Reviews Molecular Cell Biology. 8(11). |PDF|

Lein, E. S., Hawrylycz, M. J., et al. (2007). "Genome-wide atlas of gene expression in the adult mouse brain." Nature. 445: 168-176 |PubMed|PDF|Bio-IT World Commentary|